Proteomes and Proteins
A Course Jointly Organized by
The International School of Advanced BioMedicine and BioInformatics
and by
The Lipari International School for Computer Science Researchers
Lipari Island, July 9-22, 2006
The proteome is the specific
protein complement of each cell. Proteomics, the
analysis of proteomes structure and functional organization including protein
post-translation modifications and protein-protein interactions (Interactomics), represents one of the frontiers of contemporary
biomolecular and
biocomputational research. In conjunction with
Genomics, it will allow to understand how genotypes become phenotypes
(eg, the relationship between the nucleotide sequence of a gene and the
tridimensional structure of its encoded protein) as well as the dynamic
interactions between organisms and the environment, including pathological
modifications of their molecular phenotype. Besides making possible
the identification of new targets for disease diagnosis and treatment,
Proteomics will
also allow to predict ligand-receptor binding, a critical step both for a
thorough understanding of the specificity of molecular interactions and
for the discovery of new drugs.
Finally, Proteomics will uncover potential toxic side effects during drug screening thus
guiding the optimization process.
In light of this, in 2006 the International School of Advanced BioMedicine and BioInformatics and the Lipari
International School for Computer Science Researchers are jointly organizing a
course on Proteomes and Proteins, aimed at
describing the state of the art knowledge on proteomes, their dynamic
changes during the life cycle of cells and organisms, their modifications in
disease states as well as the applications of this knowledge to
Molecular Medicine,
Biotechnology and Medicinal Chemistry.
Speakers
Scientific Committee
Tutors |